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Engineering a pyridoxal 5’-phosphate supply for cadaverine production by using Escherichia coli whole-cell biocatalysis

Although the routes of de novo pyridoxal 5′-phosphate (PLP) biosynthesis have been well described, studies of the engineering of an intracellular PLP supply are limited, and the effects of cellular PLP levels on PLP-dependent enzyme-based whole-cell biocatalyst activity have not been described. To i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ma, Weichao, Cao, Weijia, Zhang, Bowen, Chen, Kequan, Liu, Quanzhen, Li, Yan, Ouyang, Pingkai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614675/
https://ncbi.nlm.nih.gov/pubmed/26490441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15630
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