Increased angiotensinogen expression, urinary angiotensinogen excretion, and tissue injury in nonclipped kidneys of two-kidney, one-clip hypertensive rats

In angiotensin II (ANG II)-dependent hypertension, there is an angiotensin type 1 receptor-dependent amplification mechanism enhancing intrarenal angiotensinogen (AGT) formation and secretion in the tubular fluid. To evaluate the role of increased arterial pressure, AGT mRNA, protein expression, and...

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Publicat a:Am J Physiol Renal Physiol
Autors principals: Shao, Weijian, Miyata, Kayoko, Katsurada, Akemi, Satou, Ryousuke, Seth, Dale M., Rosales, Carla B., Prieto, Minolfa C., Mitchell, Kenneth D., Navar, L. Gabriel
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008673/
https://ncbi.nlm.nih.gov/pubmed/27194718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00419.2015
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