ROCK/NF-κB axis-dependent augmentation of angiotensinogen by angiotensin II in primary-cultured preglomerular vascular smooth muscle cells

In angiotensin II (ANG II)-dependent hypertension, the augmented intrarenal ANG II constricts the renal microvasculature and stimulates Rho kinase (ROCK), which modulates vascular contractile responses. Rho may also stimulate angiotensinogen (AGT) expression in preglomerular vascular smooth muscle c...

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Bibliografiset tiedot
Päätekijät: Miyata, Kayoko, Satou, Ryousuke, Shao, Weijian, Prieto, Minolfa C., Urushihara, Maki, Kobori, Hiroyuki, Navar, L. Gabriel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2014
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949040/
https://ncbi.nlm.nih.gov/pubmed/24431199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00464.2013
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