Tumor necrosis factor-α suppresses angiotensinogen expression through formation of a p50/p50 homodimer in human renal proximal tubular cells

Angiotensinogen (AGT) expression in renal proximal tubular cells (RPTCs) and intrarenal tumor necrosis factor-α (TNF-α) levels are increased in hypertension and renal diseases However, the contribution of TNF-α to AGT expression in RPTCs has not been established. Therefore, the objective of the pres...

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Main Authors: Satou, Ryousuke, Miyata, Kayoko, Katsurada, Akemi, Navar, L. Gabriel, Kobori, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2010
Assuntos:
Receptors and Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957270/
https://ncbi.nlm.nih.gov/pubmed/20592241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00078.2010
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