Intracrine angiotensin II functions originate from noncanonical pathways in the human heart

Although it is well-known that excess renin angiotensin system (RAS) activity contributes to the pathophysiology of cardiac and vascular disease, tissue-based expression of RAS genes has given rise to the possibility that intracellularly produced angiotensin II (Ang II) may be a critical contributor...

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Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Ferrario, Carlos M., Ahmad, Sarfaraz, Varagic, Jasmina, Cheng, Che Ping, Groban, Leanne, Wang, Hao, Collawn, James F., Dell′Italia, Louis J.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2016
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008653/
https://ncbi.nlm.nih.gov/pubmed/27233763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00219.2016
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