Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters

Mammalian transcriptomes are complex and formed by extensive promoter activity. In addition, gene promoters are largely divergent and initiate transcription of reverse-oriented promoter upstream transcripts (PROMPTs). Although PROMPTs are commonly terminated early, influenced by polyadenylation site...

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Библиографические подробности
Опубликовано в: :Nat Genet
Главные авторы: Chen, Yun, Pai, Athma A., Herudek, Jan, Lubas, Michal, Meola, Nicola, Järvelin, Aino I., Andersson, Robin, Pelechano, Vicent, Steinmetz, Lars M., Heick Jensen, Torben, Sandelin, Albin
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008441/
https://ncbi.nlm.nih.gov/pubmed/27455346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3616
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