The TGF-β pathway is activated by 5-fluorouracil treatment in drug resistant colorectal carcinoma cells

TGF-β pathway is generally associated with the processes of metastasis, angiogenesis and EMT in cancer. Very little is known, however, about the role of TGF-β in cancer drug resistance. In this work, we show a specific activation of the TGF-β pathway in consequence of chemotherapeutic treatment in i...

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Udgivet i:Oncotarget
Main Authors: Romano, Gabriele, Santi, Ludovica, Bianco, Maria Rosaria, Giuffrè, Maria Rita, Pettinato, Mariateresa, Bugarin, Cristina, Garanzini, Cristina, Savarese, Leonilde, Leoni, Silvia, Cerrito, Maria Grazia, Leone, Biagio Eugenio, Gaipa, Giuseppe, Grassilli, Emanuela, Papa, Michele, Lavitrano, Marialuisa, Giovannoni, Roberto
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008345/
https://ncbi.nlm.nih.gov/pubmed/26956045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7895
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