The TGF-β pathway is activated by 5-fluorouracil treatment in drug resistant colorectal carcinoma cells

TGF-β pathway is generally associated with the processes of metastasis, angiogenesis and EMT in cancer. Very little is known, however, about the role of TGF-β in cancer drug resistance. In this work, we show a specific activation of the TGF-β pathway in consequence of chemotherapeutic treatment in i...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Romano, Gabriele, Santi, Ludovica, Bianco, Maria Rosaria, Giuffrè, Maria Rita, Pettinato, Mariateresa, Bugarin, Cristina, Garanzini, Cristina, Savarese, Leonilde, Leoni, Silvia, Cerrito, Maria Grazia, Leone, Biagio Eugenio, Gaipa, Giuseppe, Grassilli, Emanuela, Papa, Michele, Lavitrano, Marialuisa, Giovannoni, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008345/
https://ncbi.nlm.nih.gov/pubmed/26956045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7895
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