Ki-67 proliferation index but not mitotic thresholds integrates the molecular prognostic stratification of lower grade gliomas

Despite several molecular signatures for “lower grade diffuse gliomas” (LGG) have been identified, WHO grade still remains a cornerstone of treatment guidelines. Mitotic count bears a crucial role in its definition, although limited by the poor reproducibility of standard Hematoxylin & Eosin (H&...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Duregon, Eleonora, Bertero, Luca, Pittaro, Alessandra, Soffietti, Riccardo, Rudà, Roberta, Trevisan, Morena, Papotti, Mauro, Ventura, Laura, Senetta, Rebecca, Cassoni, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper: Pathology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008278/
https://ncbi.nlm.nih.gov/pubmed/27049832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8498
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