Better see to better agree: phosphohistone H3 increases interobserver agreement in mitotic count for meningioma grading and imposes new specific thresholds

BACKGROUND: Mitotic count on hematoxylin and eosin (H&E)–stained slides is a crucial diagnostic criterion in meningioma grading. However, mitosis assessment on H&E slides can be impaired by technical factors and by pathologist's experience. Phosphohistone H3 (PHH3) serine-10 is a mitosi...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Duregon, Eleonora, Cassenti, Adele, Pittaro, Alessandra, Ventura, Laura, Senetta, Rebecca, Rudà, Roberta, Cassoni, Paola
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Basic and Translational Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482862/
https://ncbi.nlm.nih.gov/pubmed/25646026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov002
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