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TEMOZOLOMIDE FOR RECURRENT INTRACRANIAL EPENDYMOMA OF THE ADULT: PATTERNS OF RESPONSE, SURVIVAL AND CORRELATIONS WITH MGMT PROMOTER METHYLATION

BACKGROUND: A variety of agents have been investigated with modest results in recurrent grade II and III ependymomas failing surgery and/or radiotherapy. Few data are available on the role of temozolomide (TMZ). We investigated patterns of response, outcome and correlations with MGMT promoter methyl...

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Autors principals: Soffietti, Riccardo, Bosa, Chiara, Bertero, Luca, Trevisan, Elisa, Cassoni, Paola, Morra, Isabella, Rudà, Roberta
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144649/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou209.34
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