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Dysregulation of DNA Methylation Induced by Past Arsenic Treatment Causes Persistent Genomic Instability in Mammalian Cells

The mechanisms by which arsenic-induced genomic instability is initiated and maintained are poorly understood. To investigate potential epigenetic mechanisms, in this study we evaluated global DNA methylation levels in V79 cells and human HaCaT keratinocytes at several time points during expanded gr...

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Detalhes bibliográficos
Publicado no:Environ Mol Mutagen
Main Authors: Mauro, Maurizio, Caradonna, Fabio, Klein, Catherine B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008255/
https://ncbi.nlm.nih.gov/pubmed/26581878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21987
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