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Genome Instabilities Arising from Ribonucleotides in DNA
Genomic DNA is transiently contaminated with ribonucleotide residues during the process of DNA replication through misincorporation by the replicative DNA polymerases α, δ and ε, and by the normal replication process on the lagging strand, which uses RNA primers. These ribonucleotides are efficientl...
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| Publicado no: | DNA Repair (Amst) |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5533643/ https://ncbi.nlm.nih.gov/pubmed/28629774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.06.004 |
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