Genetic variant in DNA repair gene GTF2H4 is associated with lung cancer risk: a large-scale analysis of six published GWAS datasets in the TRICL consortium

DNA repair pathways maintain genomic integrity and stability, and dysfunction of DNA repair leads to cancer. We hypothesize that functional genetic variants in DNA repair genes are associated with risk of lung cancer. We performed a large-scale meta-analysis of 123,371 single nucleotide polymorphism...

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Bibliografiske detaljer
Udgivet i:Carcinogenesis
Main Authors: Wang, Meilin, Liu, Hongliang, Liu, Zhensheng, Yi, Xiaohua, Bickeboller, Heike, Hung, Rayjean J., Brennan, Paul, Landi, Maria Teresa, Caporaso, Neil, Christiani, David C., Doherty, Jennifer Anne, Amos, Christopher I., Wei, Qingyi
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
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Original Manuscript
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008248/
https://ncbi.nlm.nih.gov/pubmed/27288692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgw070
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