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Single-Site Glycoprotein Mutants Inhibit a Late Event in Sindbis Virus Assembly

A panel of Sindbis virus mutants that were suspected to have deficiencies in one or more aspects of their replication cycles was examined in baby hamster kidney (BHK) cells. These included an amino acid deletion (ΔH230) and substitution (H230A) in the Sindbis glycoprotein E1_H230 and similar mutants...

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Pubblicato in:J Virol
Autori principali: Magliocca, Joseph, Vancini, Ricardo, Hernandez, Raquel, Brown, Dennis T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008083/
https://ncbi.nlm.nih.gov/pubmed/27412592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00948-16
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