Single-Site Glycoprotein Mutants Inhibit a Late Event in Sindbis Virus Assembly

A panel of Sindbis virus mutants that were suspected to have deficiencies in one or more aspects of their replication cycles was examined in baby hamster kidney (BHK) cells. These included an amino acid deletion (ΔH230) and substitution (H230A) in the Sindbis glycoprotein E1_H230 and similar mutants...

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Bibliographic Details
Published in:J Virol
Main Authors: Magliocca, Joseph, Vancini, Ricardo, Hernandez, Raquel, Brown, Dennis T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008083/
https://ncbi.nlm.nih.gov/pubmed/27412592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00948-16
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