Knockout of inositol-requiring enzyme 1α in pro-opiomelanocortin neurons decreases fat mass via increasing energy expenditure

Although numerous functions of inositol-requiring enzyme 1α (IRE1α) have been identified, a role of IRE1α in pro-opiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus is largely unknown. Here, we showed that mice lacking IRE1α specifically in POMC neurons (PIKO) are lean and res...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Open Biol
Main Authors: Xiao, Yuzhong, Xia, Tingting, Yu, Junjie, Deng, Yalan, Liu, Hao, Liu, Bin, Chen, Shanghai, Liu, Yong, Guo, Feifan
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Royal Society 2016
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008012/
https://ncbi.nlm.nih.gov/pubmed/27558934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160131
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla