Biphasic function of TLR3 adjuvant on tumor and spleen dendritic cells promotes tumor T cell infiltration and regression in a vaccine therapy

Successful cancer immunotherapy necessitates T cell proliferation and infiltration into tumor without exhaustion, a process closely links optimal maturation of dendritic cells (DC), and adjuvant promotes this process as an essential prerequisite. Poly(I:C) has contributed to adjuvant immunotherapy t...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Azuma, Masahiro, Takeda, Yohei, Nakajima, Hiroko, Sugiyama, Haruo, Ebihara, Takashi, Oshiumi, Hiroyuki, Matsumoto, Misako, Seya, Tsukasa
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007976/
https://ncbi.nlm.nih.gov/pubmed/27622060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1188244
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