Th22 cells control colon tumorigenesis through STAT3 and Polycomb Repression complex 2 signaling

Th22 cells traffic to and retain in the colon cancer microenvironment, and target core stem cell genes and promote colon cancer stemness via STAT3 and H3K79me2 signaling pathway and contribute to colon carcinogenesis. However, whether Th22 cells affect colon cancer cell proliferation and apoptosis r...

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Publicat a:Oncoimmunology
Autors principals: Sun, Danfeng, Lin, Yanwei, Hong, Jie, Chen, Haoyan, Nagarsheth, Nisha, Peng, Dongjun, Wei, Shuang, Huang, Emina, Fang, Jingyuan, Kryczek, Ilona, Zou, Weiping
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007968/
https://ncbi.nlm.nih.gov/pubmed/27622053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1082704
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