Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases

Heat shock factor 1 (HSF1) monitors the structural integrity of the proteome. Phosphorylation at S326 is a hallmark for HSF1 activation, but the identity of the kinase(s) phosphorylating this site has remained elusive. We show here that the dietary agent phenethyl isothiocyanate (PEITC) inhibits hea...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Dayalan Naidu, Sharadha, Sutherland, Calum, Zhang, Ying, Risco, Ana, de la Vega, Laureano, Caunt, Christopher J., Hastie, C. James, Lamont, Douglas J., Torrente, Laura, Chowdhry, Sudhir, Benjamin, Ivor J., Keyse, Stephen M., Cuenda, Ana, Dinkova-Kostova, Albena T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007788/
https://ncbi.nlm.nih.gov/pubmed/27354066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00292-16
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