Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases

Heat shock factor 1 (HSF1) monitors the structural integrity of the proteome. Phosphorylation at S326 is a hallmark for HSF1 activation, but the identity of the kinase(s) phosphorylating this site has remained elusive. We show here that the dietary agent phenethyl isothiocyanate (PEITC) inhibits hea...

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Publicado en:Mol Cell Biol
Main Authors: Dayalan Naidu, Sharadha, Sutherland, Calum, Zhang, Ying, Risco, Ana, de la Vega, Laureano, Caunt, Christopher J., Hastie, C. James, Lamont, Douglas J., Torrente, Laura, Chowdhry, Sudhir, Benjamin, Ivor J., Keyse, Stephen M., Cuenda, Ana, Dinkova-Kostova, Albena T.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007788/
https://ncbi.nlm.nih.gov/pubmed/27354066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00292-16
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