Conditions for the generation of cytotoxic CD4(+) Th cells that enhance CD8(+) CTL-mediated tumor regression

Adoptive cell therapies (ACTs) using tumor-reactive T cells have shown clinical benefit and potential for cancer treatment. While the majority of the current ACT are focused on using CD8(+) cytotoxic T lymphocytes (CTL), others have shown that the presence of tumor-reactive CD4(+) T helper (Th) cell...

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Vydáno v:Clin Transl Immunology
Hlavní autoři: Li, Kunyu, Baird, Margaret, Yang, Jianping, Jackson, Chris, Ronchese, Franca, Young, Sarah
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007627/
https://ncbi.nlm.nih.gov/pubmed/27588200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2016.46
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