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Autophagosome–lysosome fusion in neurons requires INPP5E, a protein associated with Joubert syndrome
Autophagy is a multistep membrane traffic pathway. In contrast to autophagosome formation, the mechanisms underlying autophagosome–lysosome fusion remain largely unknown. Here, we describe a novel autophagy regulator, inositol polyphosphate‐5‐phosphatase E (INPP5E), involved in autophagosome–lysosom...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5007553/ https://ncbi.nlm.nih.gov/pubmed/27340123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593148 |
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