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Shank–cortactin interactions control actin dynamics to maintain flexibility of neuronal spines and synapses

The family of Shank scaffolding molecules (comprising Shank1, 2 and 3) are core components of the postsynaptic density (PSD) in neuronal synapses. Shanks link surface receptors to other scaffolding molecules within the PSD, as well as to the actin cytoskeleton. However, determining the function of S...

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Bibliographic Details
Published in:Eur J Neurosci
Main Authors: MacGillavry, Harold D., Kerr, Justin M., Kassner, Josh, Frost, Nicholas A., Blanpied, Thomas A.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007541/
https://ncbi.nlm.nih.gov/pubmed/26547831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.13129
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