Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5

Activation of postsynaptic metabotropic glutamate receptors (mGluRs) modulates neuronal excitability and synaptic plasticity, while deregulation of mGluR signaling has been implicated in neurodevelopmental disorders. Overstimulation of mGluRs is restricted by the rapid endocytosis of receptors after...

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Bibliografische gegevens
Gepubliceerd in:Cell Rep
Hoofdauteurs: Scheefhals, Nicky, Catsburg, Lisa A.E., Westerveld, Margriet L., Blanpied, Thomas A., Hoogenraad, Casper C., MacGillavry, Harold D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815225/
https://ncbi.nlm.nih.gov/pubmed/31597090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.08.102
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