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Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5

Activation of postsynaptic metabotropic glutamate receptors (mGluRs) modulates neuronal excitability and synaptic plasticity, while deregulation of mGluR signaling has been implicated in neurodevelopmental disorders. Overstimulation of mGluRs is restricted by the rapid endocytosis of receptors after...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Scheefhals, Nicky, Catsburg, Lisa A.E., Westerveld, Margriet L., Blanpied, Thomas A., Hoogenraad, Casper C., MacGillavry, Harold D.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815225/
https://ncbi.nlm.nih.gov/pubmed/31597090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.08.102
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