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Elevation of iron storage in humans attenuates the pulmonary vascular response to hypoxia

Sustained hypoxia over several hours induces a progressive rise in pulmonary artery systolic pressure (PASP). Administration of intravenous iron immediately prior to the hypoxia exposure abrogates this effect, suggesting that manipulation of iron stores may modify hypoxia-induced pulmonary hypertens...

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Detalles Bibliográficos
Publicado en:J Appl Physiol (1985)
Main Authors: Bart, Nicole K., Curtis, M. Kate, Cheng, Hung-Yuan, Hungerford, Sara L., McLaren, Ross, Petousi, Nayia, Dorrington, Keith L., Robbins, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007321/
https://ncbi.nlm.nih.gov/pubmed/27418684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00032.2016
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