Clinical iron deficiency disturbs normal human responses to hypoxia

BACKGROUND. Iron bioavailability has been identified as a factor that influences cellular hypoxia sensing, putatively via an action on the hypoxia-inducible factor (HIF) pathway. We therefore hypothesized that clinical iron deficiency would disturb integrated human responses to hypoxia. METHODS. We...

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Udgivet i:J Clin Invest
Main Authors: Frise, Matthew C., Cheng, Hung-Yuan, Nickol, Annabel H., Curtis, M. Kate, Pollard, Karen A., Roberts, David J., Ratcliffe, Peter J., Dorrington, Keith L., Robbins, Peter A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2016
Fag:
Clinical Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887172/
https://ncbi.nlm.nih.gov/pubmed/27140401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85715
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