Contrasting effects of ascorbate and iron on the pulmonary vascular response to hypoxia in humans

Hypoxia causes an increase in pulmonary artery pressure. Gene expression controlled by the hypoxia‐inducible factor (HIF) family of transcription factors plays an important role in the underlying pulmonary vascular responses. The hydroxylase enzymes that regulate HIF are highly sensitive to varying...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Talbot, Nick P., Croft, Quentin P., Curtis, M. Kate, Turner, Brandon E., Dorrington, Keith L., Robbins, Peter A., Smith, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332205/
https://ncbi.nlm.nih.gov/pubmed/25501423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12220
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