A Hypoxia-Targeted Boron Neutron Capture Therapy Agent for the Treatment of Glioma

PURPOSE: Boron neutron capture therapy (BNCT) has the potential to become a viable cancer treatment modality, but its clinical translation has been limited by the poor tumor selectivity of agents. To address this unmet need, a boronated 2-nitroimidazole derivative (B-381) was synthesized and evaluat...

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Detaylı Bibliyografya
Yayımlandı:Pharm Res
Asıl Yazarlar: Luderer, Micah John, Muz, Barbara, de la Puente, Pilar, Chavalmane, Sanmathi, Kapoor, Vaishali, Marcelo, Raymundo, Biswas, Pratim, Thotala, Dinesh, Rogers, Buck, Azab, Abdel Kareem
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007153/
https://ncbi.nlm.nih.gov/pubmed/27401411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-016-1977-2
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