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A Hypoxia-Targeted Boron Neutron Capture Therapy Agent for the Treatment of Glioma
PURPOSE: Boron neutron capture therapy (BNCT) has the potential to become a viable cancer treatment modality, but its clinical translation has been limited by the poor tumor selectivity of agents. To address this unmet need, a boronated 2-nitroimidazole derivative (B-381) was synthesized and evaluat...
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| Publicat a: | Pharm Res |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5007153/ https://ncbi.nlm.nih.gov/pubmed/27401411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-016-1977-2 |
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