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A Hypoxia-Targeted Boron Neutron Capture Therapy Agent for the Treatment of Glioma
PURPOSE: Boron neutron capture therapy (BNCT) has the potential to become a viable cancer treatment modality, but its clinical translation has been limited by the poor tumor selectivity of agents. To address this unmet need, a boronated 2-nitroimidazole derivative (B-381) was synthesized and evaluat...
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| Publicado no: | Pharm Res |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5007153/ https://ncbi.nlm.nih.gov/pubmed/27401411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-016-1977-2 |
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