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Variants of the yeast MAPK Mpk1 are fully functional independently of activation loop phosphorylation

MAP kinases of the ERK family are conserved from yeast to humans. Their catalytic activity is dependent on dual phosphorylation of their activation loop’s TEY motif, catalyzed by MAPK kinases (MEKs). Here we studied variants of Mpk1, a yeast orthologue of Erk, which is essential for cell wall integr...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Biol Cell
मुख्य लेखकों: Goshen-Lago, Tal, Goldberg-Carp, Anat, Melamed, Dganit, Darlyuk-Saadon, Ilona, Bai, Chen, Ahn, Natalie G., Admon, Arie, Engelberg, David
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Cell Biology 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007096/
https://ncbi.nlm.nih.gov/pubmed/27413009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-03-0167
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