Variants of the yeast MAPK Mpk1 are fully functional independently of activation loop phosphorylation

MAP kinases of the ERK family are conserved from yeast to humans. Their catalytic activity is dependent on dual phosphorylation of their activation loop’s TEY motif, catalyzed by MAPK kinases (MEKs). Here we studied variants of Mpk1, a yeast orthologue of Erk, which is essential for cell wall integr...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Goshen-Lago, Tal, Goldberg-Carp, Anat, Melamed, Dganit, Darlyuk-Saadon, Ilona, Bai, Chen, Ahn, Natalie G., Admon, Arie, Engelberg, David
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007096/
https://ncbi.nlm.nih.gov/pubmed/27413009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-03-0167
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