Variants of the yeast MAPK Mpk1 are fully functional independently of activation loop phosphorylation

MAP kinases of the ERK family are conserved from yeast to humans. Their catalytic activity is dependent on dual phosphorylation of their activation loop’s TEY motif, catalyzed by MAPK kinases (MEKs). Here we studied variants of Mpk1, a yeast orthologue of Erk, which is essential for cell wall integr...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Goshen-Lago, Tal, Goldberg-Carp, Anat, Melamed, Dganit, Darlyuk-Saadon, Ilona, Bai, Chen, Ahn, Natalie G., Admon, Arie, Engelberg, David
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007096/
https://ncbi.nlm.nih.gov/pubmed/27413009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-03-0167
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