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Altered RNA processing and export lead to retention of mRNAs near transcription sites and nuclear pore complexes or within the nucleolus

Many protein factors are required for mRNA biogenesis and nuclear export, which are central to the eukaryotic gene expression program. It is unclear, however, whether all factors have been identified. Here we report on a screen of >1000 essential gene mutants in Saccharomyces cerevisiae for defec...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Paul, Biplab, Montpetit, Ben
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007094/
https://ncbi.nlm.nih.gov/pubmed/27385342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-04-0244
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