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Ethyl Pyruvate Combats Human Leukemia Cells but Spares Normal Blood Cells
Ethyl pyruvate, a known ROS scavenger and anti-inflammatory drug was found to combat leukemia cells. Tumor cell killing was achieved by concerted action of necrosis/apoptosis induction, ATP depletion, and inhibition of glycolytic and para-glycolytic enzymes. Ethyl lactate was less harmful to leukemi...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5006986/ https://ncbi.nlm.nih.gov/pubmed/27579985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161571 |
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