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Broad HIV-1 inhibition in vitro by vaccine-elicited CD8(+) T cells in African adults

We are developing a pan-clade HIV-1 T-cell vaccine HIVconsv, which could complement Env vaccines for prophylaxis and be a key to HIV cure. Our strategy focuses vaccine-elicited effector T-cells on functionally and structurally conserved regions (not full-length proteins and not only epitopes) of the...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Mutua, Gaudensia, Farah, Bashir, Langat, Robert, Indangasi, Jackton, Ogola, Simon, Onsembe, Brian, Kopycinski, Jakub T, Hayes, Peter, Borthwick, Nicola J, Ashraf, Ambreen, Dally, Len, Barin, Burc, Tillander, Annika, Gilmour, Jill, De Bont, Jan, Crook, Alison, Hannaman, Drew, Cox, Josephine H, Anzala, Omu, Fast, Patricia E, Reilly, Marie, Chinyenze, Kundai, Jaoko, Walter, Hanke, Tomáš, HIV-CORE 004 study group, the
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006719/
https://ncbi.nlm.nih.gov/pubmed/27617268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.61
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