Acceptability and tolerability of repeated intramuscular electroporation of Multi-antigenic HIV (HIVMAG) DNA vaccine among healthy African participants in a phase 1 randomized controlled trial

INTRODUCTION: Intramuscular electroporation (IM/EP) is a vaccine delivery technique that improves the immunogenicity of DNA vaccines. We evaluated the acceptability and tolerability of electroporation among healthy African study participants. METHODS: Forty-five participants were administered a DNA...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Mpendo, Juliet, Mutua, Gaudensia, Nanvubya, Annet, Anzala, Omu, Nyombayire, Julien, Karita, Etienne, Dally, Len, Hannaman, Drew, Price, Matt, Fast, Patricia E., Priddy, Frances, Gelderblom, Huub C., Hills, Nancy K.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259687/
https://ncbi.nlm.nih.gov/pubmed/32469893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233151
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