Modeling Human Leukemia Immunotherapy in Humanized Mice

The currently available human tumor xenograft models permit modeling of human cancers in vivo, but in immunocompromised hosts. Here we report a humanized mouse (hu-mouse) model made by transplantation of human fetal thymic tissue plus hematopoietic stem cells transduced with a leukemia-associated fu...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Xia, Jinxing, Hu, Zheng, Yoshihara, Satoshi, Li, Yuying, Jin, Chun-Hui, Tan, Shulian, Li, Wei, Chen, Qingfeng, Sykes, Megan, Yang, Yong-Guang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006579/
https://ncbi.nlm.nih.gov/pubmed/27394641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.06.028
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