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Human melanoma immunotherapy using tumor antigen-specific T cells generated in humanized mice
A major factor hindering the exploration of adoptive immunotherapy in preclinical settings is the limited availability of tumor-reactive human T cells. Here we developed a humanized mouse model that permits large-scale production of human T cells expressing the engineered melanoma antigen MART-1-spe...
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| Izdano u: | Oncotarget |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Impact Journals LLC
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872726/ https://ncbi.nlm.nih.gov/pubmed/26824989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7044 |
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