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TP53 mutational status is predictive of pazopanib response in advanced sarcomas

BACKGROUND: To investigate whether TP53 DNA mutational status impacts progression-free survival (PFS) in patients with advanced sarcomas (soft tissue sarcoma) treated with vascular endothelial growth factor receptors (VEGFR) inhibition. PATIENTS AND METHODS: We retrospectively reviewed 19 cases of p...

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Bibliographic Details
Published in:Ann Oncol
Main Authors: Koehler, K., Liebner, D., Chen, J. L.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006122/
https://ncbi.nlm.nih.gov/pubmed/26646755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdv598
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