Survival Outcomes by TP53 Mutation Status in Metastatic Breast Cancer

PURPOSE: To determine the significant genomic alterations in patients with metastatic breast cancer (MBC) and survival outcomes in common genotypes. PATIENTS AND METHODS: High-depth next-generation sequencing was performed for 202 genes in tumor and normal DNA from 257 patients with MBC, including 1...

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Vydáno v:JCO Precis Oncol
Hlavní autoři: Meric-Bernstam, Funda, Zheng, Xiaofeng, Shariati, Maryam, Damodaran, Senthil, Wathoo, Chetna, Brusco, Lauren, Demirhan, Mehmet Esat, Tapia, Coya, Eterovic, Agda Karina, Basho, Reva K., Ueno, Naoto T., Janku, Filip, Sahin, Aysegul, Rodon, Jordi, Broaddus, Russell, Kim, Tae-Beom, Mendelsohn, John, Mills Shaw, Kenna R., Tripathy, Debu, Mills, Gordon B., Chen, Ken
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2018
Témata:
Original Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050977/
https://ncbi.nlm.nih.gov/pubmed/30035249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.17.00245
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