Genetic deletion of TNFα inhibits ultraviolet radiation-induced development of cutaneous squamous cell carcinomas in PKCε transgenic mice via inhibition of cell survival signals

Protein kinase C epsilon (PKCε), a Ca(2+)-independent phospholipid-dependent serine/threonine kinase, is among the six PKC isoforms (α, δ, ε, η, μ, ζ) expressed in both mouse and human skin. Epidermal PKCε level dictates the susceptibility of PKCε transgenic (TG) mice to the development of cutaneous...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Carcinogenesis
Main Authors: Singh, Ashok, Singh, Anupama, Bauer, Samuel J., Wheeler, Deric L., Havighurst, Thomas C., Kim, KyungMann, Verma, Ajit K.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Original Manuscript
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006113/
https://ncbi.nlm.nih.gov/pubmed/26586792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv162
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