Genetic deletion of TNFα inhibits ultraviolet radiation-induced development of cutaneous squamous cell carcinomas in PKCε transgenic mice via inhibition of cell survival signals

Protein kinase C epsilon (PKCε), a Ca(2+)-independent phospholipid-dependent serine/threonine kinase, is among the six PKC isoforms (α, δ, ε, η, μ, ζ) expressed in both mouse and human skin. Epidermal PKCε level dictates the susceptibility of PKCε transgenic (TG) mice to the development of cutaneous...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Carcinogenesis
Autores principales: Singh, Ashok, Singh, Anupama, Bauer, Samuel J., Wheeler, Deric L., Havighurst, Thomas C., Kim, KyungMann, Verma, Ajit K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
Materias:
Original Manuscript
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006113/
https://ncbi.nlm.nih.gov/pubmed/26586792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv162
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares