Cell types differ in global coordination of splicing and proportion of highly expressed genes

Balance in the transcriptome is regulated by coordinated synthesis and degradation of RNA molecules. Here we investigated whether mammalian cell types intrinsically differ in global coordination of gene splicing and expression levels. We analyzed RNA-seq transcriptome profiles of 8 different purifie...

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Pubblicato in:Sci Rep
Autori principali: Trakhtenberg, Ephraim F., Pho, Nam, Holton, Kristina M., Chittenden, Thomas W., Goldberg, Jeffrey L., Dong, Lingsheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006053/
https://ncbi.nlm.nih.gov/pubmed/27577089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32249
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Accesso online

https://ncbi.nlm.nih.gov/pmc/articles/PMC5006053/
https://ncbi.nlm.nih.gov/pubmed/27577089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32249