Cell types differ in global coordination of splicing and proportion of highly expressed genes

Balance in the transcriptome is regulated by coordinated synthesis and degradation of RNA molecules. Here we investigated whether mammalian cell types intrinsically differ in global coordination of gene splicing and expression levels. We analyzed RNA-seq transcriptome profiles of 8 different purifie...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Trakhtenberg, Ephraim F., Pho, Nam, Holton, Kristina M., Chittenden, Thomas W., Goldberg, Jeffrey L., Dong, Lingsheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006053/
https://ncbi.nlm.nih.gov/pubmed/27577089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32249
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