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Cell types differ in global coordination of splicing and proportion of highly expressed genes

Balance in the transcriptome is regulated by coordinated synthesis and degradation of RNA molecules. Here we investigated whether mammalian cell types intrinsically differ in global coordination of gene splicing and expression levels. We analyzed RNA-seq transcriptome profiles of 8 different purifie...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Trakhtenberg, Ephraim F., Pho, Nam, Holton, Kristina M., Chittenden, Thomas W., Goldberg, Jeffrey L., Dong, Lingsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006053/
https://ncbi.nlm.nih.gov/pubmed/27577089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32249
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