Profile of Antiemetic Activity of Netupitant Alone or in Combination with Palonosetron and Dexamethasone in Ferrets and Suncus murinus (House Musk Shrew)

Background and Aims: Chemotherapy-induced acute and delayed emesis involves the activation of multiple pathways, with 5-hydroxytryptamine (5-HT; serotonin) playing a major role in the initial response. Substance P tachykinin NK(1) receptor antagonists can reduce emesis induced by disparate emetic ch...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Rudd, John A., Ngan, Man P., Lu, Zengbing, Higgins, Guy A., Giuliano, Claudio, Lovati, Emanuela, Pietra, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005416/
https://ncbi.nlm.nih.gov/pubmed/27630563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00263
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