Ataxia telangiectasia-mutated kinase deficiency exacerbates left ventricular dysfunction and remodeling late after myocardial infarction

Ataxia telangiectasia-mutated kinase (ATM), a cell cycle checkpoint protein, is activated in response to DNA damage and oxidative stress. We have previously shown that ATM deficiency is associated with increased apoptosis and fibrosis and attenuation of cardiac dysfunction early (1–7 days) following...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Am J Physiol Heart Circ Physiol
Hlavní autoři: Daniel, Laura L., Scofield, Stephanie L. C., Thrasher, Patsy, Dalal, Suman, Daniels, Christopher R., Foster, Cerrone R., Singh, Mahipal, Singh, Krishna
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2016
Témata:
Integrative Cardiovascular Physiology and Pathophysiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005283/
https://ncbi.nlm.nih.gov/pubmed/27288435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00338.2016
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky