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Ataxia telangiectasia mutated kinase deficiency impairs the autophagic response early during myocardial infarction
Ataxia telangiectasia mutated kinase (ATM) is activated in response to DNA damage. We have previously shown that ATM plays a critical role in myocyte apoptosis and cardiac remodeling after myocardial infarction (MI). Here, we tested the hypothesis that ATM deficiency results in autophagic impairment...
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| Publicat a: | Am J Physiol Heart Circ Physiol |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6087781/ https://ncbi.nlm.nih.gov/pubmed/29652546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00042.2018 |
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