Ataxia telangiectasia mutated kinase deficiency impairs the autophagic response early during myocardial infarction

Ataxia telangiectasia mutated kinase (ATM) is activated in response to DNA damage. We have previously shown that ATM plays a critical role in myocyte apoptosis and cardiac remodeling after myocardial infarction (MI). Here, we tested the hypothesis that ATM deficiency results in autophagic impairment...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Heart Circ Physiol
Egile Nagusiak: Thrasher, Patsy R., Scofield, Stephanie L. C., Dalal, Suman, Crawford, Claire C., Singh, Mahipal, Singh, Krishna
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087781/
https://ncbi.nlm.nih.gov/pubmed/29652546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00042.2018
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak